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Neuroscience research

Phosphorylated DSIP in hypoxia: a modified peptide and a specific model

Rats under simulated high-altitude conditions were assessed for sleep architecture, spatial memory and signaling after a phosphorylated DSIP intervention.

Preclinical studyPaper year: 2018Phosphorylated DSIP

01 / DESIGN

What was studied?

Rats under simulated high-altitude conditions were assessed for sleep architecture, spatial memory and signaling after a phosphorylated DSIP intervention.

02 / FINDINGS

What did the researchers report?

The modified peptide was associated with altered sleep stages, better task performance and changes in CREB-related measurements.

03 / LIMITS

How should it be interpreted?

The tested molecule was phosphorylated DSIP, not necessarily ordinary DSIP. Simulated hypoxia in rats does not establish treatment of human insomnia or cognitive impairment.

Loti Labs Peptide editorial reading note. Based on the linked source record. Methods and corrections.

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